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Oct 15, 2024 · Hemophilia B, also known as factor IX deficiency or Christmas disease, is the second most common type of hemophilia. The disorder was first reported in the medical literature in 1952 in a patient with the name of Stephen Christmas. The most well-known family with hemophilia B was that of Queen Victoria of England. May 7, 2024 · The condition is also known as Christmas disease, named after Stephen Christmas, who was a 5-year-old boy and the first person diagnosed with this disease type in 1952. Hemophilia B is caused by a mutation in the F9 gene, which creates a deficiency in a blood clotting protein called factor IX (FIX). Nov 28, 2022 · When you hear the term “Christmas disease,” you might wonder if it is somehow related to the holiday. But this alternate name for hemophilia B came about because of the first hemophilia B patient: 5-year-old Stephen Christmas. It was 1952 when the Canadian boy was diagnosed thanks to coagulation researchers, Rosemary Biggs and Robert McFarlane. This Journal has a reputation for publishing more amusing or spoof articles in their Christmas edition along with genuine research. The article about Christmas Disease by Biggs and McFarlane was published on 27th December 1952. Many people believed it was a joke article, especially as the patient was called Mr Christmas. Jan 22, 2020 · Peter Kopplin Toronto, Canada The 1952 Christmas issue of the British Medical Journal (BMJ) had an unusual but fitting article. It was titled “Christmas Disease, a condition previously mistaken for haemophilia.”1 The seminal patient was five-year-old Stephen Christmas and the title suggested an unusual lack of British reserve. Rosemary Biggs and colleagues were giving the Why did people once call hemophilia B Christmas disease? For more than 100 years, healthcare providers thought there was just one type of hemophilia. In 1952, a researcher used plasma from seven people who had hemophilia — one with the last name Christmas — to treat other people who had hemophilia. The treatment worked. It was originally named “Christmas disease” after the first person diagnosed with the disorder back in 1952. Hemophilia A is 7 times more common than hemophilia B, occurring in about 1 in 25,000 male births in US and 1 in 30,000–60,000 in India. 3,4 All races and economic groups are affected equally. Dec 8, 2023 · In addition to Christmas disease, hemophilia B is sometimes called the royal disease because a number of European royals in history are known to have either carried the gene for the disease or had ... Dec 14, 2015 · Hemophilia B is called Christmas Disease because it was named for a 5 year old boy named Christmas. He was the first patient described in a case series of 7 patients by Biggs et. al. in 1953. “He had numerous episodes of haemorrhage dating from the age of 20 months, mostly resulting from injuries during play.

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